General Organic Chemistry II (with Virtual Laboratory)

CHEM 285/3.0

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Overview

A continuation from CHEM 281/3.0 intended for students in biological sciences, and other plans taking no further courses in organic chemistry. Organic molecules and their reactions; relevance to biological systems. Illustrations using biomolecules such as carbohydrates, amino acids and proteins, lipids, and nucleic acids. The virtual laboratory provides knowledge of elementary organic syntheses.

Learning Outcomes

  • Write names of molecules from structures and vice versa. Identify and name functional groups 

  • Identify reactive sites on reagents (nucleophiles, electrophiles, acids, bases, leaving groups) 

  • Identify stereochemistry of molecules in terms of nomenclature and class of compound 

  • Predict and justify the impact of solvent and electronic effects on reactivity 

  • Predict reaction outcomes in the context of substitution and elimination reactions  

  • Add to the reactions from CHEM281 for functional group interconversions 

  • Combine functional group interconversions in more complex molecules 

  • Learn protecting group chemistry and apply to multi-step syntheses 

  • Use NMR, mass spec, and IR data to determine structures of simple compounds 

  • Explore basic experimental techniques through Labster and other lab simulations 

Textbook sections covered

Unit 1Chapter 13 - Conjugated Unsaturated Systems
Unit 2Chapter 14 - Aromatic Compounds
Unit 3Chapter 15 - Reactions of Aromatic Compounds
Unit 4Chapter 12 - Alcohols from Carbonyl Compounds
Unit 5Chapter 10 - Radical Reactions
Unit 6Chapter 16 - Aldehydes and Ketones: Nucleophilic Addition to the Carbonyl Group
Unit 7Chapter 17 - Aldehydes and Ketones II: Enols and Enolates
Unit 8Chapter 18 - Carboxylic Acids and their Derivatives
Unit 9Chapter 19 - Synthesis and Reactions of Beta Dicarbonyl Compounds
Unit 10Chapter 20 - Amines
Unit 11Chapter 20 - Carbohydrates
Unit 12Chapter 23 - Lipids
Unit 13Chapter 24 - Amino Acids and Proteins

Additional Information

NOTE: Life Sciences Honours students should not enrol in this course.